If antibiotics are ordered post-operatively, the last dose should be given < 24 hours from surgery end
Limiting the duration of antimicrobial prophylaxis as a single dose preoperative dose can reduce the risk of C. difficile disease
Cefoxitin 2g IV q6h (OR 3g IV if ≥120 kg) x 4 doses
OR
Cefazolin 2g IV q8h (OR 3g IV if ≥120 kg) x 3 doses
PLUS
Metronidazole 500mg IV q6h x 4 doses
Gentamicin 5 mg/kg x 1