Monitor QTc in patients with increased risk.

• QTc prolongation

• Dysglycemia

• Rash

• Tendinopathy and rupture

• GI upset

• Weakness exacerbation in myasthenia gravis

• CNS toxicity including confusion, psychosis

• Other QTc prolonging agents

• Divalent cations - Decreased absorption

• NSAIDs - Increase seizure risk

• Warfarin - Increased INR