Antimicrobials
Ceftriaxone

Ceftriaxone

High
N/A
$

Dosing

General Information

Empiric therapy of:

  • Bacterial meningitis

  • Nosocomial gram negative infections (except Pseudomonas)

  • Spontaneous bacterial peritonitis

  • Hospitalized community or nursing home acquired pneumonia in combination with a macrolide

  • cUTI

  • The use of ceftriaxone in the initial management of MSSA bacteraemia is controversial given the potential severity of the condition and the limited available clinical evidence to support its use.

  • Allergy/rash (immediate or delayed)

  • Cytopenias

  • Eosinophilia

  • Hepatic & renal laboratory abnormalities

  • Pseudocholelithiasis. Unclear clinical significance. Uncommonly symptomatic, but frequently by ultrasound gallbladder sludge

Antimicrobial class: Parenteral Cephalosporin - 3rd Generation

Pregnancy category: B

Average serum half life: 8 hours

Urine penetration: Therapeutic

Lung penetration: Therapeutic

CSF penetration: Therapeutic

Biliary penetration: Therapeutic