Amoxicillin
Renal

Renal

In the setting of rapidly improving/worsening renal function, calculations of CrCl are inaccurate, and dosing should be based on estimated renal function instead.

If worsening renal function, actual CrCl is likely lower than calculated.

If improving renal function, actual CrCl is likely higher than calculated CrCl.

Not On Dialysis

CrCl <10 mL/min

500mg PO q12-24h

CrCl 10 - 30 mL/min

500- 1000 mg PO q12h

CrCl >30 mL/min

500-1000mg PO q8h

Intermittent Dialysis

250-500mg po q12-24h

Take after dialysis on HD days