Antimicrobials
Rifampin

Rifampin

Low
Excellent
IV:$$$ PO:$

General Information

Prosthetic infections due to Staph aureus (in combination with other agents), Mycobacterial infections, Brucellosis

Laboratory

  •  LFTs at baseline and periodically

Clinical

  • Multiple drug-drug interactions
  •  Abnormal liver enzymes
  •  Skin rash
  • GI intolerance

Many via CYP interactions - review specific patient medications

May turn bodily secretions reddish-orange; caution in contact lens wearers

Never use as monotherapy except in latent TB