Antimicrobials
Amoxicillin-Clavulanate

Amoxicillin-Clavulanate

Medium
Excellent
$

General Information

Prophylaxis/treatment of bite wounds

Polymicrobial infections of the respiratory tract or abdomen

Skin and soft tissue infections

For prolonged therapy monitor liver enzymes and function

Hepatotoxicity due to clavulinate- usually mild, liver failure is rare

Allergy/rash (immediate or delayed), cytopenias, diarrhea. Note EBV related rash

Increased risk of rash with allopurinol

Antimicrobial class: Aminopenicillin + Beta-Lactamase inhibitor

Pregnancy category: B

Average serum half life: 1 hour

Biliary penetration: Therapeutic

Lung penetration: Therapeutic

Urine penetration: Therapeutic