Therapy for herpesviral infections (HSV and VZV) including encephalitis
Prophylaxis of herpesviral infections if recurrent disease or immunocompromised
Laboratory
Clinical
Mycophenolate can increase the acyclovir concentration
May diminish efficacy of zoster or varicella vaccine
For oral indications, Valacyclovir is the pro-drug and is more bioavailable with more convenient dosing
Antimicrobial class: Antiviral, nucleoside analogue
Pregnancy category: B
Average serum half life: 3 hours
CSF penetration: Therapeutic
Urine penetration: Therapeutic