Vancomycin PO

C difficile risk
N/A
Oral Bioavailability
None

Dosing

125mg po/ng/og q6h for 10-14 days.

Intra-colonic dose 250mg in 100mL of NS by rectal enema q6h

General Information

Only indication is in the therapy of C. difficile infection, particularly recurrent or severe disease

Possibility of accumulation in severe renal dysfunction.

Consider checking a vancomycin level in dialysis patients.

No oral absorption.

May increase vancomycin resistant Enterococci colonization in the gut.

Antimicrobial class: Glycopeptide

Pregnancy category: B

Average serum half life: 0 hours

Urine penetration: None

Lung penetration: None

CSF penetration: None

Biliary penetration: None

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