Cephalexin

C difficile risk
Medium
Oral Bioavailability
Moderate

Dosing

500-1000mg PO QID

eGFR 0 - 10eGFR 10 - 50eGFR > 50500mg PO q12-24h500mg PO q12h500-1000mg PO q6h

500mg PO q12-24h

Dose after dialysis on hemodialysis days

General Information

  • Uncomplicated skin and soft tissue infection

  • MSSA infections

  • Allergy/rash (immediate or delayed)

  • Positive Coombs

  • Cytopenias

  • Eosinophilia

  • Hepatic & renal laboratory abnormalities

Increases metformin levels

Antimicrobial class: First Generation Cephalosporin.

Pregnancy category: B

Urine penetration: Therapeutic

Lung penetration: Moderate

CSF penetration: Poor

Biliary penetration: Moderate

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