Restricted
Periodic renal, hepatic, and hematologic function tests.
Antimicrobial class: Imipenem Inhibits bacterial cell wall synthesis. Cilastatin prevents renal metabolism of imipenem by competitive inhibition of dehydropeptidase along the brush border of the renal tubules
Elimination half-life: 60 min
Lung penetration: Therapeutic
Pancreatic tissue penetration: Therapeutic
Bone penetration: Poor
Pregnancy category: Category C
Breastfeeding: Acceptable
Adapted from the Nova Scotia Health Antimicrobial Stewardship Program