Antimicrobials
Meropenem

Meropenem

Restricted

Medium
N/A

Dosing

General Information

Therapy of serious, often nosocomial infections involving resistant gram negative organisms.

During prolonged therapy, monitor renal function, liver function, CBC.

  • Immediate and delayed-type allergy

  • GI disturbance

  • Cytopenias, positive Coombs

  • Liver enzyme abnormalities

  • BCG (Intravesical): Antibiotics may diminish the therapeutic effect of BCG (Intravesical). Avoid combination.
  • BCG Vaccine (Immunization): Antibiotics may diminish the therapeutic effect of BCG Vaccine (Immunization). Monitor therapy.
  • Cholera Vaccine: Antibiotics may diminish the therapeutic effect of Cholera Vaccine. Avoid combination.
  • Estriol: Antibiotics may diminish the therapeutic effect of Estriol. Monitor therapy.
  • Valproate Products: Carbapenems may decrease the serum concentration of Valproate Products. Consider therapy modification.

Antimicrobial class: Carbapenem

Pregnancy category: B

Breastfeeding: Compatible

Average serum half life: 1 hour

Biliary penetration: Therapeutic

CSF penetration: Moderate

Lung penetration: Therapeutic

Urine penetration: Therapeutic