Clostridium difficile Infection

Clostridium difficile Infection

Clinical Considerations

  • Discontinue offending antimicrobial or de-escalate antimicrobial therapy IF possible
  • Avoid antimotility agents due to risks of toxic megacolon
  • De-prescribe unnecessary PPIs in patients with CDI

Additional Information

  • AMMI 2018 Canada C. difficile Practice Guidelines
  • IDSA 2018 C. difficile Guidelines,
  • IDSA 2021 C. difficile Focused Update
  • January 2023 TBRHSC ASP Pocket Card