As guided by Ontario COVID-19 Science Advisory Table (OSAT):
As guided by OSAT and Ontario Health recommendations:
Renal and hepatic function should be monitored at baseline and ongoing while on remdesivir.
Chloroquine or Hydroxychloroquine - risk of reduced antiviral activity (avoid coadministration).
Antimicrobial class: Adenosine nucleotide prodrug antiviral
Average serum half life: ~1 hour (metabolite ~25 hours)
Lung penetration: Therapeutic (widely distributed)