General Spectrum of Activity
CYP450 interactions ++.
Other QTc prolonging agents.
Recommend review of patient medications due to high frequency of significant interactions.
Give 1 hour pre or post meals (as food may decrease voriconazole absorption).
(Absorption is independent of gastric pH)
Restricted to Infectious Diseases (ID)/Antimicrobial Stewardship Program (ASP) and Oncology.
Antimicrobial class: Triazole antifungal, Second generation
Pregnancy category: D
Urine penetration: Poor
Lung penetration: Therapeutic
CSF penetration: Therapeutic