For treatment of serious infections caused by beta-lactam resistant gram-positive microorganisms (i.e. MRSA).
For treatment of infections caused by susceptible gram-positive microorganisms in patients who have serious allergies to first line beta-lactam antimicrobials.
Monitor renal function (serum creatinine and BUN) at baseline and minimum once weekly if stable.
Monitor trough levels (drawn ~1/2 hr prior to dose):
Other Monitoring Parameters:
Antimicrobial class: Glycopeptide
Pregnancy category: C
Average serum half life: 4-6 hours
Urine penetration: Therapeutic
Lung penetration: Therapeutic
CSF penetration: Moderate
Biliary penetration: Moderate