Antimicrobials
Oseltamivir

Oseltamivir

None
Good (70 to 90%)
$1.95/Dose $19.5/5 Days

Spectrum of Activity

Dosing

General Information

Treatment and prophylaxis of influenza

  • GI upset common (take with food to improve tolerance)
  • Rare - hepatotoxicity
  • Neuropsychiatric side effects reported

Live/Attenuated Influenza Virus Vaccine - oseltamivir may diminish therapeutic effect (ideally avoid oseltamivir 48 hrs prior or 14 days after vaccination).

Higher doses (150mg PO BID) are unlikely to provide added benefits.

Antimicrobial class: Antiviral - Neuraminidase inhibitor

Pregnancy category: C

Average serum half life: 2 hours

Lung penetration: Therapeutic