Antimicrobials
Cefepime

Cefepime

Restricted

High
N/A
$22.14/Dose $332.10/5 days

Spectrum of Activity

Dosing

General Information

  • Broad spectrum antimicrobial with gram positive and gram negative coverage including Pseudomonas.
  • Used especially for nosocomial infections involving resistant organisms.
  • Monitor renal function
  • GI intolerance
  • C. difficile colitis
  • Allergy (immediate or delayed)
  • Drug fever
  • CNS: Convulsions (especially with high doses in patients with renal failure)
  • Cytopenias
  • Hepatitis

Warfarin - anticoagulation effect may be enhanced.

Restricted to Infectious Diseases (ID)/Antimicrobial Stewardship Program (ASP) within 48 hours of being dispensed.

Antimicrobial class: 4th generation Cephalosporin

Pregnancy category: B

Average serum half life: 2 hours

Biliary penetration: Moderate

CSF penetration: Therapeutic

Lung penetration: Therapeutic

Urine penetration: Therapeutic