$1.63/Dose $32.60/5 Days


General Information

Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria.

  • Bacterial meningitis

  • Endocarditis

  • GI infections

  • Respiratory tract infections

  • Urinary tract infections

  • Bloodstream infection

  • With prolonged therapy, monitor renal, hepatic, and CBC periodically.
  • GI intolerance
  • Allergy/rash (immediate or delayed)
    • Note: Non-allergic rash is more common during viral illness
  • Drug fever
  • Phlebitis at infusion sites
  • Cytopenias
  • CNS: seizures (especially with high doses in patients with renal failure)
  • Interstitial nephritis
  • LFTs elevation
  • Allopurinol - increased risk of rash.
  • Methotrexate - concomitant use may increase methotrexate serum concentrations and increase the risk of toxicity (e.g. neutropenia).
  • Mycophenolate - may decrease serum concentrations of the active metabolite(s) of Mycophenolate.
  • Warfarin - possible increased anticoagulant effect.

Antimicrobial class: Aminopenicillin

Pregnancy category: B

Average serum half life: 1 hour

Urine penetration: Therapeutic

Lung penetration: Therapeutic

CSF penetration: Penetration into CSF occurs with inflamed meninges only

Biliary penetration: Therapeutic