Restricted
GI upset
Phlebitis
Increased SCr
AKI from crystal nephropathy
For oral indications, valacyclovir is the pro-drug, which is more bioavailable with more convenient dosing.
IV formulation restricted to Infectious Diseases (ID)/Antimicrobial Stewardship Program (ASP) and Oncology/Critical Care within 48 hours of being dispensed.
Cost:
Antimicrobial class: Antiviral agent. Nucleoside analogue.
Pregnancy category: B
Average serum half life: 2.5 hours
Urine penetration: Therapeutic
CSF penetration: Therapeutic