Infective Endocarditis (IE)
Fungal Endocarditis

Fungal Endocarditis

Possible Pathogens

Candida

Blood cultures positive in most cases of Candida

Aspergillus (less common)

  • Blood cultures rarely positive with Aspergillus
  • Culture negative IE, usually in patient with prosthetic cardiac valve

Noncardiac sites of metastatic infection may occur

Ie. endophthalmitis - requiring systemic and intraocular antifungal

Note

Consult Infectious Diseases

Recommended Treatment

Surgical replacement of infected valve

PLUS

PLUS

Once completion of initial therapy, long-term (lifelong) suppressive therapy with an oral azole is reasonable, especially in those deemed inappropriate for surgery