This species of coagulase-negative staphylococci tends to cause a substantially more virulent form of endocarditis, and causes higher prevalence of perivalvular extension of infection and metastatic infection
Monitor for development of periannular extension or extracardiac spread of infection
It is unclear whether combination treatment with vancomycin and beta lactam is superior to vancomycin alone until susceptibilities are known, but it is an option