Thorough clinical assessment should be performed to identify potential sources and metastatic sites of infection, for example:
Blood cultures should be drawn 48h after initial positive cultures and as needed thereafter until clearance is demonstrated
Positive blood cultures AND the following:
Positive blood cultures AND the following:
Infective endocarditis
Implanted prosthesis
Follow up cultures performed on specimens obtained 24 days after initial set that grow MRSA
Persistent fevers within 72 hours of initiating effective therapy
Evidence of metastatic sites of infection