Restricted
See Restricted Antimicrobial indications for use.
Blastomycosis (step down from Amphotericin).
Liver function tests
TDM through HPLC for itraconazole and bioactive hydroxy-itraconazole metabolite
Drug interactions
Hepatic enzyme abnormalities
Rash
Alopecia
GI upset
Many via CYP450. Suggest review specific patient medications.
LU code for outpatient use
Itraconazole Suspension
Antimicrobial class: Triazole antifungal
Pregnancy category: C (avoid especially in first trimester)
Average serum half life: 16 hours
Biliary penetration: Therapeutic
Lung penetration: Therapeutic