Antimicrobials
Meropenem

Meropenem

Restricted

Medium
N/A
$$

Spectrum of Activity

General Information

Restricted Antimicrobial: See approved indications for use.

  • Pathogen resistant to other antimicrobial agents
  • Documented ESBL producing organism
  • Empirical severe sepsis (suspected intra-abdominal source)
  • Immediate and delayed-type allergy

  • GI disturbance

  • Cytopenias, positive Coombs

  • Liver enzyme abnormalities

Valproic acid - Carbapenems decrease valproate levels and may decrease seizure threshold.

Antimicrobial class: Carbapenem

Pregnancy category: B

Average serum half life: 1 hour

Biliary penetration: Therapeutic

CSF penetration: Moderate

Lung penetration: Therapeutic

Urine penetration: Therapeutic