Antimicrobials
Cloxacillin

Cloxacillin

Medium
Moderate

Dosing

General Information

Treatment of MSSA infections.

  • Allergy (immediate or delayed)

  • Cytopenias

  • Eosinophilia

  • Interstitial nephritis

  • Abnormal liver enzymes

  • Phlebitis at injection site in a peripheral vein

Can increase methotrexate levels.

Decrease mycophenolate levels.

Tetracyclines can diminish cloxacillin activity.

Oral administration should be limited to non-severe infections; absorption reduced by food.

Antimicrobial class: Antistaphylococcal Penicillin

Pregnancy category: B

Average serum half life: 1 hour

Biliary penetration: Moderate

Lung penetration: Therapeutic

Urine penetration: Therapeutic