General Spectrum of Activity
Prophylaxis/treatment of bite wounds.
Polymicrobial infections of the respiratory tract or abdomen.
Skin and soft tissue infections.
For prolonged therapy, monitor liver enzymes and function.
Allergy/rash (immediate or delayed)
Note EBV related rash
Hepatotoxicity due to clavulinate - usually mild, liver failure is rare.
Increased risk of rash with allopurinol.
Note: Most gram positive organisms (e.g. Enterococci and Streptococci) do not produce a beta-lactamase and the addition of Clavulanate to Amoxicillin is not necessary.
Antimicrobial class: Aminopenicillin + Beta-lactamase inhibitor
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic