Adult Colony Stimulating Factor Consult
CSF Post-Bone Marrow Transplantation

CSF Post-Bone Marrow Transplantation

Regimen

  • At least 24 hours must have elapsed between end of chemotherapy and initiation of CSF
  • Filgrastim is usually initiated on Day +5 of bone marrow transplantation, with day 0 being the day of stem cell infusion
  • However, the start date might vary by treatment protocol
  • Weight 75kg or less: Filgrastim 300 mcg subcutaneous every 24 hours
  • Weight greater than 75kg: Filgrastim 480 mcg subcutaneous every 24 hours
  • CSF should be continued until ANC is >1500/μL for 2 days or >1000/μL for 3 days