Percutaneous drainage of abscesses preferred over surgical drainage

Risk Factors for Failure of Source Control:

• Delay in initial intervention (>24hrs)
• High illness severity (APACHE II ≥15)
• Advanced age
• Comorbidity and degree of organ dysfunction
• Low albumin level
• Poor nutritional status
• Degree of peritoneal involvement / diffuse peritonitis
• Inability to achieve adequate debridement / control of drainage
• Malignancy

Initiate as soon as diagnosis of IAI is made or highly suspected