Adult Antimicrobial Dosing: CRRT

Adult Antimicrobial Dosing: CRRT


The information in these guidelines is not intended to replace sound clinical judgement in the delivery of healthcare

Inclusion of an agent below does not indicate formulary status

If there are no clear dosage recommendations available, the pharmacist will contact the prescriber for further discussion

More Information

  • Heintz BH, Matzke GR, Dager WE. Antimicrobial dosing concepts and recommendations for critically ill adult patients receiving continuous renal replacement therapy or intermittent hemodialysis. Pharmacotherapy. 2009;29(5):562-77.
  • Hoff BM, Maker JH, Dager WE, Heintz BH. Antibiotic Dosing for Critically Ill Adult Patients Receiving Intermittent Hemodialysis, Prolonged Intermittent Renal Replacement Therapy and Continuous Renal Replacement Therapy: An Update. Annals of Pharmacotherapy. 2019;54(1):43-55.
  • Trotman RL, Williamson JC, Shoemaker DM, Salzer WL. Antibiotic dosing in critically ill adult patients receiving continuous renal replacement therapy. Clin Infect Dis. 2005;41(8):1159-66.
  • University of Nebraska Medical Center. Renal Dosage Adjustment Guidelines for Antimicrobials.