Firstline - Clinical Decisions

Guidelines

Febrile Neutropenia - Pediatric

Clinical Considerations

Definitions

Neutropenia = Absolute neutrophil count < 1500
Fever = Temperature > 100.4 ⁰F
Neutropenic fever = ANC < 1500, temperature > 100.4⁰F
Hemodynamically unstable = BP ↓ from baseline, requiring vasopressors

Etiology, Risk Factors, Common Pathogens

Patient Type

Hemodynamically Stable

Hemodynamically Unstable

Persistent Fevers Lasting ≥ 72hrs From Start of Empiric Antibiotics