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Guidelines
Non-Purulent Skin and Soft Tissue Infection (Streptococcus)

Non-Purulent Skin and Soft Tissue Infection (Streptococcus)

Empiric Treatment

Low Acuity Oral
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No signs or symptoms of systemic infection:

  • Typical cases of cellulitis (erythema, edema, tenderness, skin warmth)

Low Acuity IV
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No signs or symptoms of systemic infection:

  • Typical cases of cellulitis (erythema, edema, tenderness, skin warmth)

High Acuity ± Sepsis IV
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Presence of systemic signs and symptoms of infection:

  • Temperature >38°C or <36°C
  • Tachypnea >24 breaths/min
  • Tachycardia >90 bpm
  • WBC >12,000 or <4,000 mm3

OR

  • Evidence of penetrating trauma
  • Nasal colonization with MRSA
  • IVDU
  • Neutropenia
  • Sepsis

More Information

  1. Dennis L. Stevens, Alan L. Bisno, Henry F. Chambers, E. Patchen Dellinger, Ellie J. C. Goldstein, Sherwood L. Gorbach, Jan V. Hirschmann, Sheldon L. Kaplan, Jose G. Montoya, James C. Wade. Practice Guidelines for the Diagnosis and Management of Skin and Soft Tissue Infections: 2014 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciu296. 2014. Accessed November 11, 2019:e10-e52