Clinical Considerations

  • Inflammation of meninges covering the brain and spinal cord

  • Severe headache, neck pain and stiffness, altered mental status

  • Systemic symptoms: fever, chills, vomiting and photophobia

  • Lumbar puncture (LP) of cerebrospinal fluid (CSF) and analysis can help guide therapy before C&S results are available

    • Do not delay antibiotic initiation if the LP is delayed
  • CT scan may be required