Staphylococcus aureus (MSSA)

Staphylococcus aureus (MSSA)


General Information

  • Oxacillin
  • Cefazolin
  • Vancomycin
  • Daptomycin
  • Linezolid

Gram-positive cocci in clusters, coagulase-positive

Staphylococcus aureus is a ubiquitous organism that colonizes the skin/nares and can cause invasive disease

  • Purulent ABSSSIs
  • Bacteremia (Infectious Diseases consultation recommended)
  • Osteomyelitis
  • Endocarditis
  • Pneumonia
  • Meningitis (post-operative, TBIs)
  • Infection of prosthetic devices (e.g. heart valves, prosthetic joints)

Can assume Staphylococcus aureus is methicillin-susceptible if mecA/mecC is NOT detected