• Ampicillin/sulbactam
• Metronidazole
• Piperacillin/tazobactam
• Meropenem

Anaerobic spore forming gram positive bacilli, box-car shaped

• Environmental (soil, water) organism as well as human/animal digestive tract
• Associated with penetrating wounds with environmental exposure

• Gas gangrene/Clostridial myonecrosis
• Necrotizing skin and soft tissue infection
• Septic abortion, tubo-ovarian abscesses, uterine gas gangrene
• Intra-abdominal abscess
• Fatal bacteremia with massive exotoxin-mediated hemolysis
• Foodborne self-limited gastrointestinal illness