Burkholderia cepacia complex

Burkholderia cepacia complex


General Information

  • Meropenem
  • Minocycline
  • Ceftazidime

Aerobic, non-fermenting gram negative bacilli

  • Ubiquitous water and soil pathogen
  • Person-to-person spread has been documented, particularly among cystic fibrosis patients
  • Important pathogen in cystic fibrosis and lung transplant recipients
  • Often resistant to multiple antibiotics
  • Antimicrobial therapy should be guided by susceptibility testing whenever possible
  • Treatment options are often limited
  • Chronic infection with B. cepacia complex is associated with an accelerated decline in pulmonary function and shortened survival in cystic fibrosis