Antimicrobials
Foscarnet

Foscarnet

Restricted

N/A
N/A
~$3/vial

Spectrum of Activity

General Information

  • Renal function( 24-hour creatinine clearance)
  • CBC
  • Potassium
  • Calcium
  • Magnesium
  • Phosphorus
  • Renal insufficiency
  • Headache
  • Hypokalemia
  • Hypocalcemia
  • Hypomagnesemia
  • Hypophosphatemia
  • Nausea, vomiting, diarrhea
  • Anemia
  • Granulocytopenia
  • Fever

Foscavir

  • Distribution: Vd: ~0.5 L/kg; up to 28% of cumulative IV dose may be deposited in bone
  • Protein binding: 14% to 17%
  • Metabolism: Biotransformation does not occur
  • Half-life elimination: ~3 to 4 hours; terminal: ~88 hours (due to bone deposition)
  • Excretion: Urine (≤28% as unchanged drug)