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Tier 3
Myopathy, muscle weakness
Rhabdomyolysis
Cubicin, Cubicin-RF
Distribution: 0.1 L/kg
Protein binding: 90% to 93%
Metabolism: Minor
Half-life elimination: 8-9 hrs
Excretion: Urine (78%; primarily as unchanged drug); feces (5.7%)
Clearance: 8.3-9 mL/hr/kg
Inactivated by pulmonary surfactant and therefore insufficient for pulmonary infection