Guidelines
Hematology-Oncology/Bone Marrow Transplant-Related Infections

Hematology-Oncology/Bone Marrow Transplant-Related Infections

Definition

Single temperature ≥ 38.3°C (101°F) or ≥ 38.0°C (100.4°F) over 1-hour period

≤ 500 neutrophils/mcL or < 1000 neutrophils/mcL with a predicted decline to < 500/mcL over next 48 hrs

More Information

  1.  Taplitz RA et al. J Clin Oncol 2018;36:3043-3054.
  2. Baden LR et al. NCCN 2021.
  3. Los-Arcos I et al. Infection 2021;49(2):215-231.
  4. Hill JA et al. Blood 2018;131(1):121
  5. Stewart AG et al. Ther Adv Infectious Dis 2021;8. 
  6. Freifeld AG et al. Clin Infect Dis 2011;52(4):e56-93. 
  7. Boeckh M et al. Blood 2006;107: 1800-1805. 
  8. Boeckh M et al. Blood 2009;113(23):5711-5719. 
  9. Zaia JA. Bone Marrow Transplant 2002;29(8):633-638.
  10. Maertens J et al. J Antimicrob Chemother 2016:71(9);2397–2404.
  11. Aguilar-Guisado M et al. Lancet Haematol 2017:4(12):e573-e583.
  12. Le Clech L et al. Infect Dis 2018;50(7):539-549.