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Guidelines
Pneumocystis jirovecii Pneumonia Prophylaxis

Pneumocystis jirovecii Pneumonia Prophylaxis

Background

Pneumocystis jirovecii Pneumonia (PJP) is a potentially life-threatening opportunistic infection that occurs in immunocompromised patients

  • Lack of clear guidance regarding which non-HIV infected patients require PJP prophylaxis
  • Use the risk categories below to help determine whether patient should receive prophylaxis
  • Weigh risks vs benefits; decision to initiate PJP prophylaxis should be made on an individual basis

More Information

  1. Stern A et al. Prophylaxis for PCP pneumonia in non-HIV immunocompromised patients. Cochrane Database Syst Review. 2014.
  2. Taplitz RA et al. Antimicrobial prophylaxis for Patients with Cancer-related Immunosuppression. J Clin Oncology. 2018;36(30):3043-3056.
  3. Martin SI et al. Pneumocystis Pneumonia in Solid Organ Transplantation. Am J Trans. 2013;13:272-279.
  4. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 8th edition.