UTI: Non-Pregnant Without a Urinary Catheter

UTI: Non-Pregnant Without a Urinary Catheter

Clinical Considerations

In a symptomatic patient, urinalysis (UA) and urine cultures (cx) should be obtained BEFORE giving antibiotics

Do NOT collect urine cultures in absence of signs or symptoms of UTI

UTI is unlikely in absence of pyuria (UA WBC ≤ 10 cells/mm³); pyuria without urinary symptoms is not diagnostic of UTI

Indicates colonization of urinary tract or catheter, or contamination

More Information

  • Fluoroquinolones have been removed as an empiric treatment due to low rates of E. coli susceptibilities
  • Resistance rates 30-40% at Scripps Hospitals
  1. Gupta K et al. Practice Guidelines for Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women. CID 2011;52(5):3103.
  2. Bartlett JG et al. Johns Hopkins ABX Guide: Diagnosis and Treatment of Infectious Diseases (2nd Ed.). 2010.
  3. Drekonja DM et al. JAMA Intern Med. 2013;173(1):62-68.