Diabetic Foot Infections (DFIs)

Diabetic Foot Infections (DFIs)

Clinical Considerations

Diagnose infection based on:

  • Presence of purulent secretions, OR
  • Presence of ≥2 classic symptoms/signs of inflammation:
    • Erythema
    • Warmth
    • Tenderness
    • Pain
    • Induration

Typically polymicrobial with aerobic gram-positive cocci, aerobic gram-negative rods, and anaerobes

No concern for anaerobes; anaerobic coverage is not necessary

Hold antibiotics prior to cultures

Obtain post-debridement cultures and de-escalate based upon susceptibilities

More Information

Lipsky BA, Berendt AR, Cornia PB et al. 2012 Infectious Diseases Society of America Clinical Practice Guidelines for the Diagnosis and Treatment of Diabetic Foot Infections. Clin Infect Dis 2012;54(12):132-173.