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Antimicrobials
Cefotaxime

Cefotaxime

Restricted

High
N/A

Spectrum of Activity

General Spectrum of Activity
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General Information

  • Bacterial meningitis
  • Pneumonia (in combination with a macrolide)
  • Intra-abdominal infection including SBP
  • Musculoskeletal i.e. septic arthritis
  • Urinary tract infection
  • Rash
  • Localized phlebitis at injection site
  • Allergy
  • Positive Coombs test
  • Neutropenia
  • Abnormalities in liver enzymes
  • Diarrhea
  • CDI

Antimicrobial class: 3rd Generation Cephalosporin

Pregnancy category: B

Average serum half life: 1.5 hours

Urine penetration: Therapeutic

Lung penetration: Therapeutic

CSF penetration: Therapeutic

Biliary penetration: Moderate