Antimicrobials
Foscarnet

Foscarnet

Restricted

N/A
N/A
$$$$/day

Spectrum of Activity

General Information

  • Ganciclovir resistant CMV

Laboratory:

  • Electrolytes: calcium, magnesium, phosphorous, potassium
  • BMP and CBC
  • Electrolyte disturbances: hypocalcemia, hypokalemia, hypomagnesemia, hypophosphatemia, hyperphosphatemia
  • Nephrotoxicity
  • Anemia
  • Paresthesias
  • Seizures

Hydration (750-1000mL) required prior to first infusion and 500-1000mL with subsequent doses, dependent on dosing.  Ensure patient able to tolerate hydration.

Antimicrobial class: Antiviral - pyrophosphate agent

Pregnancy category: C

Average serum half life: 4 hours

Urine penetration: Therapeutic

CSF penetration: Variable/Moderate