Antimicrobials
Benzathine benzylpenicillin/Penicillin G benzathine (Bicillin L-A)

Benzathine benzylpenicillin/Penicillin G benzathine (Bicillin L-A)

Low
N/A
$$$$/dose (syphilis) $$$/dose (pharyngitis)

Spectrum of Activity

Dosing

General Information

Preferred treatment for all stages of syphilis, except in neurosyphilis (aqueous PCN G infusion instead).

Documented Streptococcal pharyngitis.

  • Allergy (anaphylaxis) and other rash
  • Rare: Cytopenias, Positive Coombs, Eosinophilia

No major interactions.

Antimicrobial class: Penicillin, long-acting

Pregnancy category: B

Average serum half life: 1-4 weeks

CSF penetration: Poor

Urine penetration: Therapeutic