Low (20 to 40%)

Spectrum of Activity


General Information

  • Not the equivalent of an oral ceftriaxone
  • Due to low bioavailability, amoxicillin or amoxicillin-clavulanate preferred when sensitive for upper respiratory infections
  • Can consider for UTI when 1st/2nd generation cephalosporins are not sensitive

Clinical improvement and culture/sensitivity.

No major lab abnormalities.

Most common:

  • Diarrhea (up to 19%)
  • Rash (up to 8%) - mostly in children < 2 y/o

Aluminum and magnesium containing antacids decrease cefdinir absorption. Separate by 2 hours.

Cost based on dose 600mg/day.

Antimicrobial class: 3rd Generation Cephalosporin

Pregnancy category: B

Average serum half life: 1.7 hours

Urine penetration: Therapeutic

Lung penetration: Therapeutic

CSF penetration: Poor