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Antimicrobials
Ceftazidime-Avibactam (Avycaz)

Ceftazidime-Avibactam (Avycaz)

Restricted

High
N/A
$$$$/day

Spectrum of Activity

General Spectrum of Activity
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General Information

  • Reserved for patients with little or no alternative treatment options
  • Management of documented CRE infection
  • Allergy (immediate & delayed)
  • Positive direct coombs test
  • GI side effects
  • Pruritis

Medication cost calculated per day (24 hours) of therapy for the average adult dose (70kg) of 2.5g IV q8h.

Antimicrobial class: Cephalosporin combination

Pregnancy category: B

Average serum half life:

  • Ceftazidime: 2.76 to 3.27 hours
  • Avibactam: 2.22 to 2.71 hours

Urine penetration: Therapeutic