Ceftaroline is a new broad-spectrum cephalosporin with a spectrum of activity similar to ceftriaxone, but with activity against MRSA.
Gram positive
- Staphylococcus aureus (MSSA and MRSA)
- Streptococci
- Coagulase-negative Staphylococci
Gram negative
- Most Enterobacteriaceae
- H. influenzae
- M catarrhalis
- Pasteurella spp
Anaerobes
Does not cover
- Enterococci
- B. fragilis
- Pseudomonas and other more resistant gram negatives
- ESBL or AmpC producing Enterobacteriaceae
- Listeria
- Acinetobacter