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Antimicrobials
Ceftaroline

Ceftaroline

Restricted

High
N/A
$$$$/day

Spectrum of Activity

General Spectrum of Activity
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General Information

  • Complicated skin/skin structure infections
  • Community acquired bacterial pneumonia
  • Salvage for sustained MRSA bacteremia/endocarditis/osteomyelitis
  • Positive Coombs
  • GI side effects
  • Allergy (immediate & delayed)
  • C. difficile
  • Neurotoxicity in setting of renal dysfunction

Medication cost calculated per day (24 hours) of therapy for the average adult dose (70kg) of 600mg IV q12h.

Antimicrobial class: Parenteral Cephalosporin - 5th Generation

Pregnancy category: B

Average serum half life: 1.6 ± 0.38 hours (single dose); 2.66 ± 0.4 hours (multiple dose)

Urine penetration: Therapeutic