Broad spectrum agent with anti-pseudomonal activity. Covers Gram-negative anaerobes and does not need to be used in combination with metronidazole.
Used for severe infections including:
Allergy/rash (immediate or delayed)
Cytopenias- esp. thrombocytopenia
Eosinophilia
Interstitial nephritis
Abnormal liver enzymes
Incr. levels of methotrexate.
Medication cost calculated per day (24 hours) of therapy for the average adult dose (70kg) of 3.375g q8h.
Antimicrobial class: Ureidopenicillin with a beta-lactamase inhibitor
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: Therapeutic
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Therapeutic
Antimicrobials
