Antimicrobials
Fosfomycin

Fosfomycin

Restricted

Low
Moderate
$$$/day

Spectrum of Activity

General Information

  • Urinary Tract Infection, especially involving ESBL producing organisms
  • Off label - Prostatitis                                                    
  • Not approved for: pyelonephritis, bacteremia, patients with nephrostomy tubes or renal stones
  • GI upset, especially diarrhea
  • Headache

No significant interactions.

Medication cost calculated per day (24 hours) of therapy for the average adult dose (70kg) of 3 gm PO.

Antimicrobial class: Phosphonic acid derivative

Pregnancy category: B

Average serum half life: 6 hours

Urine penetration: Therapeutic